If you are overwhelmed with the new Legendary Mayfly or Rosetta Memetic Specializations and don’t know which ones are best suited for you in the game, I’ve got you covered with my Once Human Prismverse’s Clash best Memetic Specializations to use for solo players and teams guide.
For players who don’t know, Once Human Prismverse’s Clash has introduced 24 new Memetic Specializations, 12 of which fall under the Legendary Mayfly category and the remaining 12 under the Legendary Rosetta.
While the previous Memetic Specializations were mainly focused on Crafting, Mining, Utility, and Base Building, the new Memetic Specializations give you offensive and defensive benefits that, if chosen correctly, can give you an edge over your opponents.
So, to ensure you don’t choose the wrong Memetic Specialization and waste your fragments to reset, keep reading my Once Human Prismverse’s Clash best Memetic Specializations to use guide.
Best new Memetic Specialization for solo players in Once Human Prismverse’s Clash
While you get the new Memetic Specializations irrespective of the faction, belonging to a particular faction will guarantee the new Memetic Specializations at Levels 5, 20, and 40.
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Check out my Prismverse’s Clash new Memetic Specialization tier list.
Moreover, since almost every player has to join the Mayfly or the Rosetta, I have shared the recommended Memetic Specializations under their respective factions.
Mayfly faction
The best Memetic Specialization as a solo player belonging to the Mayfly faction is:
| Memetic Specialization | Description | When it unlocks? |
| Judgment Coherence Injection | Unlock new formulas: Gene Extractor, Judgement Coherence Injection When holding the Gene Extractor, defeating Deviants yields gene fragments based on enemy types. These fragments can be used to craft the Gene Coherence Injection for enhancing crafting abilities. The Coherence status ends after taking damage equal to 70% of your Max HP. After using the Judgement Coherence Injection, each enemy defeated grants 1 Coherence, with the following effects based on the materials used. Deviant Fragment: At 10 Coherence, Status DMG +10%. Anima Fragment: At 10 Coherence, Weapon DMG +10%. Starlith: At 30 Coherence, enter Beyond Mode, consuming 1 Coherence per attack, dealing 50 Sanity DMG to players, and DMG equal to 10% of Max HP to non-player enemies (up to 5,000). Exit Beyond Mode when Coherence is depleted. Matterlith: At 30 Coherence, Roll Stamina Consumption +50%, Roll Speed +30%, DMG Reduction during rolling increased to 80%, and summon a Flamethrower Trap that deals damage equal to 1,000% Psi Intensity over 5s. | Level 5 |
| Lightning Gene | Unlock new formulas: Lightning Gene. A special item to enhance the Gene Coherence and unlock its advanced capabilities. In combat, automatically select a random enemy within 20 meters every 10s, generating a lightning strike beneath them after a 3s delay, dealing damage equal to 4,000% Psi Intensity. | Level 20 |
| Lightning Gene Fabric | Unlocks new recipe: Lightning Gene Fabric. Used when making equipment, the equipment will gain the following effects: Critical damage reduction +3% If this equipment is a top, additional effect is obtained: When in the synchronized state, when attacked, a lightning strike is generated at the attacker’s feet with a delay of 3 seconds, causing indiscriminate damage of 4000% Psi Intensity (cooldown 30s) | Level 40 |
Rosetta faction
The best Memetic Specialization as a solo player belonging to the Rosetta faction is:
| Memetic Specialization | Description | When it unlocks? |
| Rosetta Firepower Drone | Unlock new formula: Rosetta Firepower Drone. The Rosetta Firepower Drone can be summoned at any time. The drone has mid-range shooting capabilities. The special advanced effects depend on the crafting materials used. | Level 5 |
| Focus Module | Unlock new recipe: Focus Module Special items that can be used to strengthen the drone, unlocking advanced abilities. Collection drone: When the drone is mining in the contested zone, there is a chance to obtain 10-100 barrels of Crude Oil from the ground. Firepower Drone: Unstable bomber effect can be triggered when the drone attacks. Exploration Drone: Gliding stamina consumption is reduced by 50%. During gliding, a random enemy within 20m will be automatically marked every 4 seconds. Territory Drone: After the drone has accumulated 10 hits, it will provide 5% Weapon Damage and Sanity DMG bonus to all friendly players within 15m, which lasts for 10 seconds and can be stacked up to 3 times | Level 20 |
| Armor Module | Unlocks new recipe: Armor Module. Special items that can be used to strengthen the drone, unlocking advanced abilities. When the drone has no shield, it will automatically consume 3 electronic components every 30 seconds, allowing the drone to gain 6000 shield points. | Level 40 |
When it comes to the Level 20 upgrade, you can also go for Speedy Module as the Firepower Drone unlocks the electric shock skill, which allows it to rush towards enemies within the attack range and paralyze them for 3 seconds.
Three seconds is more than enough for you to take out other players.
However, I personally think the Focus Module will be best as it triggers Unstable Bomber, and there are many Mods that greatly increase your damage whenever the Unstable Bomber effect is triggered.
Maybe, it is still not yet the time to let of JAWS.
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Best new Memetic Specialization for teams in Once Human Prismverse’s Clash
If you are playing in a team of random players or friends and are going to do most of the Prism Deviant Securement in a team with other players, here’s the best Memetic Specialization path for you:
Mayfly faction
| Memetic Specialization | Description | When it unlocks? |
| Elysium Coherence Injection | Unlock new formulas: Gene Extractor, Elysium Coherence Injection When holding the Gene Extractor, defeating Deviants yields gene fragments based on enemy types. These fragments can be used to craft the Gene Coherence Injection for enhancing both defensive and offensive abilities. The Coherence status ends after taking damage equal to 70% of your Max HP. After using the Elysium Coherence Injection, staying in any territory for 3s will grant you 1 Coherence, with the following effects based on the materials used: Deviant Fragment: At 10 Coherence, unlock Double Jump and Aerial Sprint abilities within your territory. Anima Fragment: At 10 Coherence, Attack of all allied turrets and traps within the territory +50%. Starlith: At 30 Coherence, convert all Coherence to Ascension, increasing Psi Intensity by 1% per stack but reducing Attack by 0.5%. Each attack consumes one stack of Ascension. Matterlith: At 30 Coherence, while in the territory, Stamina Consumption -30%, Roll Speed +30%, and Tactical Item DMG +30%. | Level 5 |
| Extreme Gene | Unlock new formulas: Extreme Gene. A special item to enhance the Gene Coherence and unlock its advanced capabilities. The Coherence status termination condition changes to total damage taken reaching 150% of Max HP. When HP is below 50%, Max Load +50. When HP is below 30%, Weapon DMG +15%, Tactical Item DMG +15%. When HP is below 10%, trigger a healing effect, recovering 1% of Max HP for each unused point of Max Load(20s cooldown) | Level 20 |
| Extreme Gene Fabric | Unlock new formula: Extreme Gene Fabric Used when making equipment, the equipment will gain the following effects: Weakness damage reduction +3% If this equipment is a top, additional effect is obtained: When the synchronization state is released, the invincibility effect is obtained, and the Weapon DMG, Sanity DMG, and Tactical Item DMG are reduced to 0, which lasts for 2s. | Level 40 |
Rosetta faction
| Memetic Specialization | Description | When it unlocks? |
| Rosetta Territory Drone | Unlock new formula: Rosetta Territory Drone. The Rosetta Territory Drone can be summoned at any time. When the player is in territory, the territory drone can unlock long-range shooting capabilities, and the attack power of all friendly turrets and traps in the territory will be increased by 50%. The special advanced effects depend on the crafting materials used. | Level 5 |
| Focus Module | Unlock new recipe: Focus Module Special items that can be used to strengthen the drone, unlocking advanced abilities. Collection drone: When the drone is mining in the contested zone, there is a chance to obtain 10-100 barrels of Crude Oil from the ground. Firepower Drone: Unstable bomber effect can be triggered when the drone attacks. Exploration Drone: Gliding stamina consumption is reduced by 50%. During gliding, a random enemy within 20m will be automatically marked every 4 seconds. Territory Drone: After the drone has accumulated 10 hits, it will provide 5% Weapon Damage and Sanity DMG bonus to all friendly players within 15m, which lasts for 10 seconds and can be stacked up to 3 times | Level 20 |
| Armor Module | Unlocks new recipe: Armor Module. Special items can be used to strengthen the drone, unlocking advanced abilities. When the drone has no shield, it will automatically consume 3 electronic components every 30 seconds, allowing the drone to gain 6000 shield points. | Level 40 |
For the second upgrade, you can also go with the Wide-Area Module as with the Territory Drone and the said upgrade, when a drone is in a territory, it will automatically generate a spherical shield every 30 seconds, which can absorb 5000% of the drone’s attack damage.
Those are the best Memetic Specializations I think you should be using. If you have any other new Memetic Specialization path that you think would be even better, please share it in the comments.
That concludes my Once Human Prismverse’s Clash best Memetic Specialization path for solo and team players. If the article helped, please consider buying me a Coffee to help me create more content. You can also share the guide with your friends or leave a comment.
